Natto Zyme Report
Research Report
NATTO-ZYME
TM
Natto-Zyme is one of the most significant discoveries in natural medicine during the past sev-
eral decades. It is also, as of the date this information sheet was prepared, not yet very much main-
stream. In fact, it is still a fairly scarce item. Certainly the chain stores and superstores do not have
it, and very, very few community pharmacies even know what it is all about. To the best of our
knowledge we are introducing the only branded version of it as a stand alone product.
What’s it all about?
Natto-Zyme attacks clots in the blood and destroys them. It also acts as a blood thinner and as a
cholesterol lowering device. is a thousand year old Japanese secret derived from soy
beans now available in the US in this exciting new natural break-through formula.
Natto-Zyme should not be taken if a patient is already taking one of the following prescription
drugs:
• Blood thinners, such as Coumadin
• Statin Drugs
Background and Historical Information
According to Dr. Marcus Laux, our problems are really a dysfunction within the circulatory
system. “The blood becomes overcrowded with excess clotting factors, proteins, fats, and other
substances that create irritation, plaque build up, and potentially clots that can starve the heart.”
He further adds that the real culprit is oxidation of LDL, and maintains that it can be thought of as a
mugging by thieving free radicals.
According to the American Thrombosis Association, up to 20 million cases of blood clot re-
lated illnesses are reported each and every year.
Other analyses indicate that a blood clot is the body’s natural response to a cut, scrape, injury
or trauma. To stop the blood loss, your body manufactures a protein called fibrin. Fibrin helps pre-
vent blood loss by sealing off the damaged blood vessels. After the bleeding danger is over a blood
clot is no longer needed so the body produces a special enzyme called plasmen to target and dis-
solve clots.
Unfortunately, while the body manufactures over 20 enzymes to clot the blood, only one en-
zyme is produced to dissolve blood clots and that is plasmen.
As we age, the body’s ability to produce plasmen and break down blood clots significantly
declines.
So what is the answer? Doctors prescribe blood thinners – or taking an aspirin a day.
According to numerous US and British studies, taking aspirin does not significantly reduce
one’s risk of having a heart problem.
Page 1 of 3
The Japanese Experience
While US doctors administer dangerous and costly blood thinning drugs, like cumadin, to clear
up blood clots, the Japanese are using all-natural foods to safely dissolve dangerous blood clots.
One of them is known as “natto” for short. Natto-Zyme is made by adding the bacteria bascillus-
natto to soy beans and allowing the mixture to ferment.
Natto has the uncanny ability to liquify blood clots and prevent them from occurring in the first
place. In other words natto helps :
• improve overall circulation
• maintain normal blood pressure
• relieve pain and discomforts caused by blood clots
• restore muscle strength
• enhance our body’s natural ability to fight clots
Natto-Zyme is the final formulation that produces all these wonderful results. And so it may be
considered as the ultimate blood flow formula.
Here are some alarming statistics...
In the coming twelve months in America alone:
• 725,000 persons will die of heart related calamities. (Tim Russert was one.)
• 167,000 folks will meet their maker due to deadly blood clots in the brain
• More than 200,000 people will die due to blood clots in the legs.
What is the solution? Natto-Zyme.
Some famous doctors review of natto.
Tests run at Oklahoma State University, as well as Miyazaki Medical College in Japan, conclu-
sively prove that actually attacks and destroys the clots in your blood. Unlike
most research studies the subjects were not rats or other laboratory animals but real live humans.
The healthy male and female volunteers— all between the ages of 21 and 25 were each adminis-
tered 200 grams of Natto before breakfast. Then through a series of blood plasma tests, the research-
ers tracked the ability of their bodies to dissolve blood clots. The results, on average, the volunteers
ELT (a measure of how long it takes to dissolve a blood clot) dropped by 48% within two hours of
treatment and their bodies RETAINED THIS ENHANCED ABILITY TO DISSOLVE BLOOD
CLOTS FOR UP TO 8 FULL HOURS.
“In all my years of research as a professor of cardiology and pulmonary medicine
sents the most exciting development in the prevention and treatment of cardiovascular related prob
lems. We have finally found a potent natural agent that can help thin and dissolve clots effectively
with relative safety and without side effects.” —Martin Milner, MD. Center for Natural Medicine,
Portland, Oregon.
Dr. Ralph Holsworth, DO, leading researcher for the clinical studies documenting the ethnicity
of Nattokinase, is so impressed by what he has found he says “I have dedicated the rest of my life to
the research of
tients this significantly. Taking
Page 2 of 3
Please note: Nattokinase is the original form of the blending of natto with soy. Our Natto-Zyme
is a 1:1 ratio to the Nattokinase.
Jonathan Wright, MD, adds “the literature about natto and
first patient I asked to try it had a rapid and dramatic response. While this was likely an unusually
good result,
According to Dr. Michael Culter, MD, “what most people don’t know is that
natural ACE inhibitor. This means it blocks the creation and function of angiotensin converting en
zymes”.
Other applications of
The case of a patient named Cecilia can shed light on how much more value Natto could provide.
Cecilia began experiencing pain in her lower abdomen. However, it wasn’t accompanied by vom-
iting, constipation, diarrhea, nausea, fever, or any other symptoms of abdominal problems.
After an examination, her doctor ruled out appendicitis or diverticulitis.
Fortunately a nurse remembered that Cecelia had a history of blood clots and wondered if that
could be the source of her pain. Blood clots can starve tissues of the blood they need.
Cecelia began a course of treatment with Natttokanise (the generic version of Natto-Zyme). The
results, her unexplainable pain disappeared in less than 20 minutes!
Moments after taking the first Natto capsule, Cecelia felt a tingling sensation in her abdomen and
in less than 20 minutes all of the pain disappeared.
But after 3 or 4 hours the pain returned. So Cecelia took another Natto capsule and the pain van-
ished again.
As long as Cecilia was taking the Natto product, she remained pain-free. Once her doctors deter-
mined that clotting was at the root of Cecelia’s problems they put her on this natural clot prevention
program.
Cecilia’s story is becoming more common every day. In fact, according to Dr. Martin Milner,
Center for Natural Medicine in Portland, Oregon “Chronic fatigue is very difficult to treat. What is
usually ignored is circulatory impairment and access clotting. It’s a new thought in alternative medi
cine that someone is chronically fatigued because their blood clots excessively and they’re not get
ting enough blood (and consequently, enough oxygen and nutrients) to their tissues.”
What’s a major culprit in poor blood flow? It’s an overabundance of fibrin, the thread-like sub-
stance needed to clot blood. Excess fibrin can interfere with oxygen flow and the delivery of nutri-
ents to cells. It can also prevent speedy removal of cell waste products. As a result a wide range of
health maladies can ensue.
Summary and Conclusions
Natto-Zyme, made from a thousand year old Japanese natural ace inhibitor, root of excess fibrin,
and therefore destroys clots in the blood. Both Japanese and American experience have aptly demon-
strated both the science and benefits of the use of this product. For more readings on this subject, the
reader may go to the attached list of references.
References
• Albert CM, Gaziano JM, Willet WC, Manson JE. Nut Consumption and decreased risk of sudden cardiac
death in the Physicians’ Health Study. Arch Intern Med. 2002; 162:1382-1387.
• Blau S, Kohen R, Bass P, Rubinstein. Relation between colonic inflammation severity and total low-
molecular– weight antioxidant profiles in experimental colitis. Dig Dis Sci. 2002;45:1180-1187.
• Enstrom JE, Kanim LE, Klein MA.. Vitamin C intake and mortality among a sample of the united states
population. Epidemiology. 1992;3:194-202.
• Fuhrman B, Rosenblat M, Hayek T, Coleman R, Aviram M. Ginger extract consumption reduces plasma
cholesterol, inhibits LDL oxidation and attenuates development of atherosclerosis in atherosclerotic, apoli-
poprotein E-deficient mice. J . 2000;130:1124-1131.
• Gardner S, Schnieder E, Granberry MC, Carter IR. Combination Therapy with low-dose lovastatin and nia-
cin as effective as higher dose lovastatin. Pharmacotherapy. 1996;16:419-423.
• Gouni-Berthold I, Berthold HK. Policosanol: Clinical pharmacology and therapeutic significance of a new
lipid-lowering agent. Am Heart J. 2002;143:356-365.
• Homocysteine Lowering Trialists’ Collaboration. Lowering blood homocysteine with folic acid based sup-
plements: meta-analysis of randomized trials. BMJ. 1998;316:894-898.
• Janikula M. Policosanol: a new treatment for cardiovascular disease? Alt Med Rev. 2002;7(3):203-217.
• Mercier J, Gavend MR, Dessaigne S. Effect of inositol and its derivatives on hypercholesterolemic rabbits.
Cong Union Therap Intern (Brussels). 1963;8:11.
• Normen L, Dutta P, Lia A, Anderson H. Soy sterol esters and betasitostanol esters as inhibitors of choles-
terol absorption in human small bowel. Am J Clin . 1999;69:114-1150.
• Nygard O, Norderhaug JE, Refsum H, Ueland PM, Farstad M, Vollset SE. Plasma homocysteine levels
and mortality in patients with coronary artery disease. . 1997;337:230-236
• Petrowicz O, Gebhardt R, Donner M, Shwandt P, Kraft K. Effects of artichoke leaf extract on lipoprotein
metabolism in vitro and in vivo. Atherosclerosis. 1997;129:147
• Putter M, Grotemyer KH, Wurthwein G, et al. Inhibition of smoking-induced platelet aggregation by aspi-
rin and pycnogenol. Thromb Res. 1999;95:155-161.
• Ridker PM, Hennekens CH, Buring JE, Rifai N. C-Reactive protein and other markers of inflammation in
the prediction of cardio vascular disease in women. 200;342:836-843.
• Schnyder G, Roggi M, Flammer Y, Pin R, Hess OM. Effect of homocysteine lowering therapy with folic
acid, vitamin B(12), and vitamin B(6) on clinical outcome after precutaneous coronary intervention: the
Swiss Heart study: a randomized controlled trial. JAMA. 2002;288:973-979.
• Salonen JT, Nyyssonen K, Korpela H, Tumilehto J, Seppanen R, Salonen R. High store iron levels are as-
sociated with excess risk of myocardial infraction in Eastern Finnish men. Circulation. 1992;86:803-811.
• Stampfer MJ, Malimow MR, Willet WC, et al. A prospective study of plasma homocyst(e)ine and risk of
myocardial infraction in US physicians. JAMA. 1992;268:877-881.
• Teede HJ, Dalais FS, Kotsopoulos D, Liang YL, Davis S, McGrath BP. Dietary soy has both beneficial
and potentially adverse cardiovascular effects: a placebo controlled study in men and Postmenopausal
women. J Clin Endocrinol Meta. 2001;86:3053-3060.
• Throne Research. Pantethine ( Monograph) Alt Med Rev. 1998;379-381.
• Throne Research. Plant sterols and sterolins (Monograph). Alt Med Rev. 2001;6:203-206.
• Welsh AL, Ede M. Inositol hexanicotinate for improve nicotinic acid therapy. Int Record Med. 1961;174:9
-15
NATTO-ZYME
TM
Natto-Zyme is one of the most significant discoveries in natural medicine during the past sev-
eral decades. It is also, as of the date this information sheet was prepared, not yet very much main-
stream. In fact, it is still a fairly scarce item. Certainly the chain stores and superstores do not have
it, and very, very few community pharmacies even know what it is all about. To the best of our
knowledge we are introducing the only branded version of it as a stand alone product.
What’s it all about?
Natto-Zyme attacks clots in the blood and destroys them. It also acts as a blood thinner and as a
cholesterol lowering device. is a thousand year old Japanese secret derived from soy
beans now available in the US in this exciting new natural break-through formula.
Natto-Zyme should not be taken if a patient is already taking one of the following prescription
drugs:
• Blood thinners, such as Coumadin
• Statin Drugs
Background and Historical Information
According to Dr. Marcus Laux, our problems are really a dysfunction within the circulatory
system. “The blood becomes overcrowded with excess clotting factors, proteins, fats, and other
substances that create irritation, plaque build up, and potentially clots that can starve the heart.”
He further adds that the real culprit is oxidation of LDL, and maintains that it can be thought of as a
mugging by thieving free radicals.
According to the American Thrombosis Association, up to 20 million cases of blood clot re-
lated illnesses are reported each and every year.
Other analyses indicate that a blood clot is the body’s natural response to a cut, scrape, injury
or trauma. To stop the blood loss, your body manufactures a protein called fibrin. Fibrin helps pre-
vent blood loss by sealing off the damaged blood vessels. After the bleeding danger is over a blood
clot is no longer needed so the body produces a special enzyme called plasmen to target and dis-
solve clots.
Unfortunately, while the body manufactures over 20 enzymes to clot the blood, only one en-
zyme is produced to dissolve blood clots and that is plasmen.
As we age, the body’s ability to produce plasmen and break down blood clots significantly
declines.
So what is the answer? Doctors prescribe blood thinners – or taking an aspirin a day.
According to numerous US and British studies, taking aspirin does not significantly reduce
one’s risk of having a heart problem.
Page 1 of 3
The Japanese Experience
While US doctors administer dangerous and costly blood thinning drugs, like cumadin, to clear
up blood clots, the Japanese are using all-natural foods to safely dissolve dangerous blood clots.
One of them is known as “natto” for short. Natto-Zyme is made by adding the bacteria bascillus-
natto to soy beans and allowing the mixture to ferment.
Natto has the uncanny ability to liquify blood clots and prevent them from occurring in the first
place. In other words natto helps :
• improve overall circulation
• maintain normal blood pressure
• relieve pain and discomforts caused by blood clots
• restore muscle strength
• enhance our body’s natural ability to fight clots
Natto-Zyme is the final formulation that produces all these wonderful results. And so it may be
considered as the ultimate blood flow formula.
Here are some alarming statistics...
In the coming twelve months in America alone:
• 725,000 persons will die of heart related calamities. (Tim Russert was one.)
• 167,000 folks will meet their maker due to deadly blood clots in the brain
• More than 200,000 people will die due to blood clots in the legs.
What is the solution? Natto-Zyme.
Some famous doctors review of natto.
Tests run at Oklahoma State University, as well as Miyazaki Medical College in Japan, conclu-
sively prove that actually attacks and destroys the clots in your blood. Unlike
most research studies the subjects were not rats or other laboratory animals but real live humans.
The healthy male and female volunteers— all between the ages of 21 and 25 were each adminis-
tered 200 grams of Natto before breakfast. Then through a series of blood plasma tests, the research-
ers tracked the ability of their bodies to dissolve blood clots. The results, on average, the volunteers
ELT (a measure of how long it takes to dissolve a blood clot) dropped by 48% within two hours of
treatment and their bodies RETAINED THIS ENHANCED ABILITY TO DISSOLVE BLOOD
CLOTS FOR UP TO 8 FULL HOURS.
“In all my years of research as a professor of cardiology and pulmonary medicine
sents the most exciting development in the prevention and treatment of cardiovascular related prob
lems. We have finally found a potent natural agent that can help thin and dissolve clots effectively
with relative safety and without side effects.” —Martin Milner, MD. Center for Natural Medicine,
Portland, Oregon.
Dr. Ralph Holsworth, DO, leading researcher for the clinical studies documenting the ethnicity
of Nattokinase, is so impressed by what he has found he says “I have dedicated the rest of my life to
the research of
tients this significantly. Taking
Page 2 of 3
Please note: Nattokinase is the original form of the blending of natto with soy. Our Natto-Zyme
is a 1:1 ratio to the Nattokinase.
Jonathan Wright, MD, adds “the literature about natto and
first patient I asked to try it had a rapid and dramatic response. While this was likely an unusually
good result,
According to Dr. Michael Culter, MD, “what most people don’t know is that
natural ACE inhibitor. This means it blocks the creation and function of angiotensin converting en
zymes”.
Other applications of
The case of a patient named Cecilia can shed light on how much more value Natto could provide.
Cecilia began experiencing pain in her lower abdomen. However, it wasn’t accompanied by vom-
iting, constipation, diarrhea, nausea, fever, or any other symptoms of abdominal problems.
After an examination, her doctor ruled out appendicitis or diverticulitis.
Fortunately a nurse remembered that Cecelia had a history of blood clots and wondered if that
could be the source of her pain. Blood clots can starve tissues of the blood they need.
Cecelia began a course of treatment with Natttokanise (the generic version of Natto-Zyme). The
results, her unexplainable pain disappeared in less than 20 minutes!
Moments after taking the first Natto capsule, Cecelia felt a tingling sensation in her abdomen and
in less than 20 minutes all of the pain disappeared.
But after 3 or 4 hours the pain returned. So Cecelia took another Natto capsule and the pain van-
ished again.
As long as Cecilia was taking the Natto product, she remained pain-free. Once her doctors deter-
mined that clotting was at the root of Cecelia’s problems they put her on this natural clot prevention
program.
Cecilia’s story is becoming more common every day. In fact, according to Dr. Martin Milner,
Center for Natural Medicine in Portland, Oregon “Chronic fatigue is very difficult to treat. What is
usually ignored is circulatory impairment and access clotting. It’s a new thought in alternative medi
cine that someone is chronically fatigued because their blood clots excessively and they’re not get
ting enough blood (and consequently, enough oxygen and nutrients) to their tissues.”
What’s a major culprit in poor blood flow? It’s an overabundance of fibrin, the thread-like sub-
stance needed to clot blood. Excess fibrin can interfere with oxygen flow and the delivery of nutri-
ents to cells. It can also prevent speedy removal of cell waste products. As a result a wide range of
health maladies can ensue.
Summary and Conclusions
Natto-Zyme, made from a thousand year old Japanese natural ace inhibitor, root of excess fibrin,
and therefore destroys clots in the blood. Both Japanese and American experience have aptly demon-
strated both the science and benefits of the use of this product. For more readings on this subject, the
reader may go to the attached list of references.
References
• Albert CM, Gaziano JM, Willet WC, Manson JE. Nut Consumption and decreased risk of sudden cardiac
death in the Physicians’ Health Study. Arch Intern Med. 2002; 162:1382-1387.
• Blau S, Kohen R, Bass P, Rubinstein. Relation between colonic inflammation severity and total low-
molecular– weight antioxidant profiles in experimental colitis. Dig Dis Sci. 2002;45:1180-1187.
• Enstrom JE, Kanim LE, Klein MA.. Vitamin C intake and mortality among a sample of the united states
population. Epidemiology. 1992;3:194-202.
• Fuhrman B, Rosenblat M, Hayek T, Coleman R, Aviram M. Ginger extract consumption reduces plasma
cholesterol, inhibits LDL oxidation and attenuates development of atherosclerosis in atherosclerotic, apoli-
poprotein E-deficient mice. J . 2000;130:1124-1131.
• Gardner S, Schnieder E, Granberry MC, Carter IR. Combination Therapy with low-dose lovastatin and nia-
cin as effective as higher dose lovastatin. Pharmacotherapy. 1996;16:419-423.
• Gouni-Berthold I, Berthold HK. Policosanol: Clinical pharmacology and therapeutic significance of a new
lipid-lowering agent. Am Heart J. 2002;143:356-365.
• Homocysteine Lowering Trialists’ Collaboration. Lowering blood homocysteine with folic acid based sup-
plements: meta-analysis of randomized trials. BMJ. 1998;316:894-898.
• Janikula M. Policosanol: a new treatment for cardiovascular disease? Alt Med Rev. 2002;7(3):203-217.
• Mercier J, Gavend MR, Dessaigne S. Effect of inositol and its derivatives on hypercholesterolemic rabbits.
Cong Union Therap Intern (Brussels). 1963;8:11.
• Normen L, Dutta P, Lia A, Anderson H. Soy sterol esters and betasitostanol esters as inhibitors of choles-
terol absorption in human small bowel. Am J Clin . 1999;69:114-1150.
• Nygard O, Norderhaug JE, Refsum H, Ueland PM, Farstad M, Vollset SE. Plasma homocysteine levels
and mortality in patients with coronary artery disease. . 1997;337:230-236
• Petrowicz O, Gebhardt R, Donner M, Shwandt P, Kraft K. Effects of artichoke leaf extract on lipoprotein
metabolism in vitro and in vivo. Atherosclerosis. 1997;129:147
• Putter M, Grotemyer KH, Wurthwein G, et al. Inhibition of smoking-induced platelet aggregation by aspi-
rin and pycnogenol. Thromb Res. 1999;95:155-161.
• Ridker PM, Hennekens CH, Buring JE, Rifai N. C-Reactive protein and other markers of inflammation in
the prediction of cardio vascular disease in women. 200;342:836-843.
• Schnyder G, Roggi M, Flammer Y, Pin R, Hess OM. Effect of homocysteine lowering therapy with folic
acid, vitamin B(12), and vitamin B(6) on clinical outcome after precutaneous coronary intervention: the
Swiss Heart study: a randomized controlled trial. JAMA. 2002;288:973-979.
• Salonen JT, Nyyssonen K, Korpela H, Tumilehto J, Seppanen R, Salonen R. High store iron levels are as-
sociated with excess risk of myocardial infraction in Eastern Finnish men. Circulation. 1992;86:803-811.
• Stampfer MJ, Malimow MR, Willet WC, et al. A prospective study of plasma homocyst(e)ine and risk of
myocardial infraction in US physicians. JAMA. 1992;268:877-881.
• Teede HJ, Dalais FS, Kotsopoulos D, Liang YL, Davis S, McGrath BP. Dietary soy has both beneficial
and potentially adverse cardiovascular effects: a placebo controlled study in men and Postmenopausal
women. J Clin Endocrinol Meta. 2001;86:3053-3060.
• Throne Research. Pantethine ( Monograph) Alt Med Rev. 1998;379-381.
• Throne Research. Plant sterols and sterolins (Monograph). Alt Med Rev. 2001;6:203-206.
• Welsh AL, Ede M. Inositol hexanicotinate for improve nicotinic acid therapy. Int Record Med. 1961;174:9
-15
